Mexidol 125 mg 30 tablets | Anti Anxiety Relief | Reduces tension & Emotional burnout | Enhances memory | Protects brain cells from oxygen deficiency (hypoxia)

Always use the medicine exactly as recommended by your treating physician. If you are unsure, consult your physician. The initial dose is 1–2 tablets (125–250 mg) 1–2 times daily, gradually increasing until a therapeutic effect is achieved. The stated adult oral dose is 1–2 tablets (125–250 mg) 3 times daily; the maximum daily dose is 6 tablets (750 mg).

For treatment of the consequences of acute cerebrovascular disorders, including after transient ischemic attacks, the tablets are prescribed after a course of the medicine as an intravenous or intramuscular solution. For children with attention-deficit/hyperactivity disorder, including hyperactivity, impaired attention, and impulsivity, the leaflet states 1 tablet (125 mg) twice daily. Your treating physician may change the dose.

For oral use, swallow the tablet whole with water; do not break it. Treatment duration is 2–8 weeks. For children treated for attention-deficit/hyperactivity disorder, the leaflet states 6 weeks. For people with ischemic heart disease, it states at least 6–8 weeks. Repeat courses, on a physician’s recommendation, are preferably in spring and autumn. For alcohol-withdrawal syndrome, the stated duration is 5–7 days; treatment is stopped gradually by reducing the dose over 2–3 days. Do not use this translation to select a dose or treatment course.

The phrase buy mexidol 125mg usa is a search term, not a dosing instruction. The specific regimen must be determined by a qualified healthcare professional.

Indications stated in the supplied leaflet

The Russian-language leaflet states use for: consequences of acute cerebrovascular disorders, including after transient ischemic attacks, in the initial/subcompensation stage as preventive courses; mild traumatic brain injury and its consequences; encephalopathies of various origins (circulatory, metabolic, post-traumatic, or mixed); autonomic dystonia syndrome; mild cognitive impairment of atherosclerotic origin; anxiety disorders in neurotic and neurotic-like conditions; ischemic heart disease as part of combination therapy; alcohol-withdrawal syndrome in chronic alcoholism with predominantly neurotic and autonomic-vascular disorders and delayed post-withdrawal disorders; conditions after acute intoxication with antipsychotic medicines; asthenic conditions and prevention of somatic diseases under extreme factors and stress; and attention-deficit/hyperactivity disorder in children, including hyperactivity, impaired attention, and impulsivity.

These are statements from the supplied foreign-language leaflet and are not U.S. indications. If you searched for buy mexidol 125mg usa, consult a licensed healthcare professional about applicable local requirements before considering any use.

Composition

Each tablet contains 125.0 mg of ethylmethylhydroxypyridine succinate. Excipients: lactose monohydrate, povidone K-30, and magnesium stearate. Film coating: hypromellose, titanium dioxide, lactose monohydrate, macrogol, and triacetin. The leaflet states that the product contains lactose.

Contraindications

Do not use, according to the supplied leaflet, if you are allergic to ethylmethylhydroxypyridine succinate or any other ingredient; have acute liver or kidney dysfunction; are under 6 years of age; are pregnant or breastfeeding; or have intolerance to certain sugars (the product contains lactose). The source leaflet says use is contraindicated during pregnancy and breastfeeding.

Warnings and precautions

Consult your treating physician before use. Tell your physician if you have intolerance to certain sugars because the product contains lactose. Use in children younger than 6 years is not recommended in the supplied leaflet because of insufficient efficacy and safety data. If you are pregnant, breastfeeding, think you may be pregnant, or plan to become pregnant, consult a healthcare professional; the leaflet states the medicine is contraindicated during pregnancy and breastfeeding. Use caution when driving or operating machinery or performing tasks requiring quick psychomotor reactions.

A search for buy mexidol 125mg usa cannot replace a clinician’s assessment of contraindications, interactions, or local regulatory status.

Pack and dosage form

Film-coated tablets, 125 mg; 30 tablets per package, supplied with instructions for use.

Possible adverse reactions

As with other medicines, the supplied leaflet reports possible adverse reactions, although they do not occur in everyone. Very rare reported reactions (up to 1 in 10,000 people) include a serious allergic reaction such as difficulty breathing or swelling of the face, neck, lips, tongue, or throat (angioedema); itchy allergic rash (urticaria); drowsiness; headache; dry mouth; nausea; stomach/epigastric pain, burning, or discomfort; heartburn; flatulence; diarrhea; rash; itching; and skin redness. Seek medical attention for a severe or unusual reaction.

Pharmacotherapeutic group

Antioxidant agent, as stated in the supplied leaflet.

Interactions

Tell your treating physician about medicines you take, have recently taken, or may take. The supplied leaflet says the medicine may be used with medicines for somatic diseases and may enhance the effects of sedatives or sleeping medicines (for example, diazepam or midazolam), antidepressants, medicines for anxiety (including phenibut), antiepileptic medicines (including valproate or lamotrigine), and antiparkinsonian medicines. It also states that the medicine reduces the toxic effects of ethyl alcohol. Do not infer that a combination is appropriate for you; obtain professional advice.

Pharmacodynamics stated in the supplied leaflet

The leaflet identifies ethylmethylhydroxypyridine succinate as the active ingredient and classifies it as an antioxidant. It describes proposed activity related to oxidative processes in nervous and cardiovascular diseases and alcohol or medicine intoxication, and states that the medicine may increase resistance to damaging factors associated with shock, tissue hypoxia, ischemia, cerebrovascular disorders, and certain intoxications. These statements are translated from the supplied leaflet and are not independent evidence of clinical benefit in the United States.

Storage

Store at 2–25 °C, according to the supplied leaflet.

Appearance

Round, biconvex, film-coated tablets, white to white with a yellowish tint; the supplied leaflet notes a characteristic odor may be present.

Pharmacokinetics stated in the supplied leaflet

The leaflet states that the medicine is rapidly absorbed after oral use; the maximum concentration after doses of 400–500 mg is 3.5–4.0 μg/mL; it distributes rapidly in organs and tissues; average retention after oral use is 4.9–5.2 hours; it is metabolized in the liver by glucuronidation; and it is mainly excreted in urine as metabolites, with a smaller amount unchanged. The leaflet reports an oral half-life of 2.0–2.6 hours and says excretion is most intensive during the first 4 hours. These translated statements are not a U.S. prescribing recommendation.

Overdose and missed dose

The supplied leaflet says overdose may cause drowsiness or insomnia and that symptoms generally resolve on their own within 24 hours; seek medical care for pronounced symptoms. If a dose is missed, do not take a double dose to make up for it; take the next dose at the usual time. If you have questions about use, contact a healthcare professional.